Definitely go with fully synthetic for multiple benefits. Unless you are burning some oil between changes, initially try standard 10-30 or even 5-30 and see how your vehicle performs. If oil is "consumed" in 5,000 miles, then the high mileage synthetic would be the better choice.
I have had five Toyota pickups (still have two). At around 10,000 miles I have switched to full synthetic on all of them.
REASON: The engine is fully broken in at 10,000 miles and all debris has settled out. Switching to the lower friction, lower wear synthetic oil ( I use Mobil 1) results in about 10% better gas mileage (my experience on all five of them).
I change oil and filter between 5,000 and 7,500 miles. None of my trucks burned oil, so no topping off between drains was necessary. I have never had any engine problems in several hundreds of thousands of miles.